小林研究室│広島大学大学院 理学研究科 数理分子生命理学専攻 数理計算理学講座複雑系数理研究室

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原著論文

 

S. S. Lee, Positioning of polarity formation by extracellular signal during asymmetric cell division, Journal of Theoretical Biology. (accepted)

K. Ito, T. Ezaki, S. Suzuki, R. Kobayashi, Y. Hara, S. Nakata, :"Synchronization of Two Self-Oscillating Gels Based on Chemo-Mechanical Coupling", The Journal of Physical Chemistry B, 120(11), pp 2977-2983, 2016,  [Link]

K. Sugihara, K. Nishiyama, S. Fukuhara, A. Ueyama, S. Arima, R. Kobayashi, A. Kohn-Luque, N. Mochizuki, T. Suda, H. Ogawa and H. Kurihara : “Autonomy and non-autonomy of angiogenic cell movements revealed by experiment-driven mathematical modeling”, Cell Reports, 13(9) : 1814-1827 (2015)  [Link]

S. S. Lee, T. Shibata, "Self-organization and advective transport in the cell polarity formation for asymmetric cell division", Journal of Theoretical Biology, 382(7), 1-14. (2015)  [Link]

T. Umedachi, S. Horiki, R. Kobayashi and A. Ishiguro, "Enhancing adaptability of amoeboid robot by synergetically coupling two decentralized controllers inspired by true slime mold", Adaptive Behavior, 23(2), 109-121, 2015.  [Link]

T. Umedachi, K. Ito, A. Ishiguro, "Soft-bodied amoeba-inspired robot that switches between qualitatively different behaviors with decentralized stiffness control", Adaptive Behavior, 23(2), 97-108, 2015 . [Link]

S. Kuroda, K. Ituki, Y. Tanaka, A. Ishiguro, R. Kobayashi, T. Nakagaki, "Common mechanics of mode switching in locomotion of limbless and legged animals", Journal of Royal Society Interface, 11(95):20140205, 2014.   [Link]

M. Iwamoto, D. Ueyama, R. Kobayashi, "The Advantage of Mucus for Adhesive Locomotion in Gastropods", Journal of Theoretical Biology 353,133-141, 2014.   [Link]

T. Kano, R. Kobayashi, Akio Ishiguro, "Decentralized control scheme for adaptive earthworm locomotion using continuum-model-based analysis", Advanced Robotics 28(3), 197-202, 2014.   [Link]

T. Umedachi, R. Idei, K. Ito, A. Ishiguro, "True-slime-mould-inspired hydrostatically coupled oscillator system exhibiting versatile behaviours", Bioinspiration & Biomimetics, 8(3):035001, 2013  [Link]

Y. Nishigami, M. Ichikawa, T. Kazama, R. Kobayashi, T Shinmen, K. Yoshikawa and S. Sonobe, "Reconstruction of Active Regular Motion in Amoeba Extract: Dynamic Cooperation between Sol and Gel States", PLoS ONE 8(8):e70317, 2013.  [Link]

T. Umedachi, R. Idei, K. Ito, A. Ishiguro :"A Fluid-filled Soft Robot That Exhibits Spontaneous Switching among Versatile Spatio-temporal Oscillatory Patterns Inspired by True Slime Mold", Aritificial Life, 19(1):67-78, 2013 [Link]

T. Kano, T. Sato, R. Kobayashi, A. Ishiguro, "Local relfexive mechanisms essential for snakes' scaffold-based locomotion" Bioinspiration & Biomimetics 7(4):046008, 2012.  [Link]

T. Umedachi, R. Idei, T. Nakagaki, R. Kobayashi, A. Ishiguro, "Fluid-Filled soft-Bodied Amoeboid Robot Inspired by Plasmodium of True Slime mold", Advanced Robotics 26(7):693-707, 2012.  [Link]

Y. Tanaka, K. Ito, T. Nakagaki, R. Kobayashi :"Mechanics of peristaltic locomotion and role of anchoring", Journal of The Royal Society Interface, Published online before print August 10, 2011,  [Link]

D. Owaki, S. Ishida, A. Tero, K. Ito, K. Nagasawa, A. Ishiguro :"An Oscillator Model That Enables Motion Stabilization and Motion Exploration by Exploiting Multi-rhythmicity", Advanced Robotics, Vol 25, 1139-1158, (2011). [Link]

T. Latty, K. Ramsch, K. Ito, T. Nakagaki, D. Sumper, M. Middendorf, M. Beekman: “Structure and formation of ant transportation networks”, Journal of The Royal Society Interface , Vol. 8, 1298-1306. (2011)  . [Link]

K. Ito, D. Sumpter, T. Nakagaki :"Risk management in spatio-temporally varying field by true slime mold", Nonlinear Theory and Its Applications, IEICE, Vol. 1, 26-36 (2010).  [Link]

T. Kazama, Y. Ichihashi, S. Murata and H. Tsukaya: "The Mechanism of Cell Cycle Arrest Front Progression Explained by a KLUH/CYP78A5-dependent Mobile Growth Factor in Developing Leaves of Arabidopsis thaliana", Plant Cell Physiol. 51: 1046-1054(2010).  [Link]

M. Akiyama, A. Tero, R. Kobayashi :"A mathematical model of cleavage", Journal of theoretical biology, Vol. 264, 84-94 (2010).  [Link]

A. Tero, S. Takagi, T. Saigusa, K. Ito, D. P. Bebber, M. D. Fricker, K. Yumiki, R. Kobayashi, T. Nakagaki : "Rules for Biologically Inspired Adaptive Network Design", Science, Vol. 327, 439-442 (2010). [Link]

 

A. Tero, T. Nakagaki, T. Kazutaka, Y. Kenji and R. Kobayashi : “A method inspired by Physarum for solving the Steiner problem”, International Journal of Unconventional Computing (2009)

 

K. Ito, Y. Nishiura,
"Intermittent switching for three repulsively coupled oscillators",

Phys. Rev. E, Vol 77, 036224 (2008)

 

A. Tero, K. Yumiki, R. Kobayashi, T. Saigusa and T. Nakagaki : “Flow-network adaptation in Physarum amoebae”, Theory In Biosciences, 127 : 89-94 (2008)

 

A. Tero, R. Kobayashi and T. Nakagaki : “A mathematical model for adaptive transport network in path finding by the true slime mold”, J. Theor. Biol., 244 : 553-564 (2007)

 

T. Nakagaki, M. Iima, T. Ueda, Y. Nishiura, T. Saigusa, A. Tero, R. Kobayashi and K. Showalter : “Minimum-risk path finding by an adaptive amoebal network”, Phys. Rev. Lett., 99 : 068104- (2007)

 

M. Sueda, A. Katsuki, M. Nonomura, R. Kobayashi and Y. Tanimoto : “Effects of High Magnetic Field on Water Surface Phenomena”, J. Phys. Chem. C, 111 : 14389-14393 (2007)

 

A. Tero, R. Kobayashi and T. Nakagaki : “Physarum solver: -a biologically inspired method of road-network navigation-”, Physica A, 363 : 115-119 (2006)

 

R. Kobayashi, A. Tero and T. Nakagaki : “Mathematical model for rhythmic protoplasmic movement in the true slime mold”, J. Math. Biol., 53 : 273-286 (2006)

 

野々村 真規子、小林 亮 : 「マランゴニ対流の2次元モデルで見られるパターンとダイナミクス」、応用数理、16(3) : 20-30 (2006)

 

A. Tero, R. Kobayashi and T. Nakagaki : “A coupled-oscillator model with a conservation law for the rhythmic amoeboid movements of plasmodial slime molds”, Physica D, 205 : 125-135 (2005)

 

R. Kobayashi and J. A. Warren : “Modeling the formation and dynamics of polycrystals in 3D”, Physica A, 356 : 127-132 (2005)

 

T. Yanagita, Y. Nishiura and R. Kobayashi : “Signal propagation and failure in one-dimensional FitzHugh-Nagumo equations with periodic stimuli”, Phys. Rev. E, 036226 : 1-4 (2005)

 

H. Haga, C. Irahara, R. Kobayashi, T. Nakagaki and K. Kawabata : “Collective movement of epithelial cells on a collagen gel substrate”, Biophysical Journal, 88 : 2250-2256 (2005)

 

T. Nakagaki, R. Kobayashi, T. Ueda and Y. Nishiura : “Obtainning multiple separate food sources: Behavioural intelligence in the Physarum plasmodium”, Proc. R. Soc. Lond. B, 271 : 2305-2310 (2004)

 

M. Nonomura, R. Kobayashi, Y. Nishiura and M. Shimomura : “Periodic Precipitation during Droplet Evaporation on a Substrate”, J. Phys. Soc. Jpn., 72(10) : 2468-2471 (2003)

 

J. A. Warren, R. Kobayashi, A. E. Lobkovsky and W. C. Carter : “Extending phase field models of solidification to polycrystalline materials”, Acta Materialia, 51 : 6035-6058 (2003)

 

和田 成生、小林 亮 : 「膨潤赤血球の体積減少に伴う形状変化の数値シミュレーション」、日本機械学会論文集(A編)、69-677 : 14-21 (2003)

 

J. A. Warren, R. Kobayashi and W. C. Carter : “Modeling Grain Boundaries Using a Phase-field Technique”, J. Cryst. Growth, 211 : 18-20 (2000)

 

R. Kobayashi, J. A. Warren and W. C. Carter : “A Continuum Model of Grain Boundaries”, Physica D, 140 : 141-150 (2000)

 

小林 亮、柳田 達雄、上田 肇一 : 「粉粒体の偏析現象に対する数理的アプローチ」、粉体工学会誌、37(9) : 50-56 (2000)

 

R. Kobayashi and Y. Giga : “Equations with Singular Diffusivity”, J. Statist. Phys., 95 : 1187-1220 (1999)

 

R. Kobayashi : “A Numerical Approach to Three-Dimensional Dendritic Solidification”, Experimental Mathematics, 3(1) : 59-81 (1994)

 

R. Kobayashi : “Modeling and Numerical Simulations of Dendritic Crystal Growth”, Physica D, 63(3) : 410-423 (1993)

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総説・解説等

小林 亮 : 「生物のロコモーションに学ぶ制御法 --粘菌からロボットへ--」、医学のあゆみ、253(12) : 1153-1157 (2015)

 

小林 亮 : 「生物に学ぶ自律分散制御 --粘菌からロボットへ--」、計測と制御、54 : 236-241 (2015)

 

小林 亮 : 「粘菌の経路探索における最適化」、日本ロボット学会誌、32(6) : 530-535 (2014)

 

小林 亮 : 「フェーズフィールド法のおもしろさ」、計算工学、15(2) : 2287-2290 (2010)

 

T. Nakagaki, A. Tero, R. Kobayashi, I. Onishi and T. Miyaji : “Computational ability of cells based on dynamics and adaptability”, New Generation Computing, Ohmsha-Springer, 27(1) : 57-81 (2009)

 

小林 亮 : 「アメーバに学ぶ最短経路探索法」、数学セミナー、日本評論社、47(5) : 20-21 (2008)

 

手老 篤史、小林 亮、中垣 俊之 : 「アメーバの迷路解きに学ぼう」、数理科学、(535) : 7-11 (2008)

 

手老 篤史、中垣 俊之、小林 亮 : 「アメーバに学ぶ経路探索の方法」、Materials Integration、20(5) : 55-60 (2007)

 

小林 亮、手老 篤史、中垣 俊之 : 「粘菌による迷路の解法」、細胞工学、26(7) : 769-773 (2007)

 

中垣 俊之、手老 篤史、小林 亮 : 「粘菌の作る輸送ネットワークのダイナミクス」、第21回生体・生理工学シンポジウム論文集 : 97-100 (2006)

 

小林 亮 : 「樹枝状結晶の形づくり」、形の科学百科事典、朝倉出版 : 305-306 (2004)

 

小林 亮、中垣 俊之 : 「真性粘菌変形体の運動の数理モデル」、数理解析研究所講究録、1305 : 8-14 (2003)

 

中垣 俊之、小林 亮 : 「粘菌変形体の流路ネットワ-クの形態形成」、数理解析研究所講究録、1305 : 1-7 (2003)

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Proceedings

A. Ishiguro, T. Umedachi, T. Kitamura, T. Nakagaki and R. Kobayashi : “A fully decentralized morphology control of an amoeboid robot by exploiting the law of conservation of protoplasmic mass”, Proceedings of IROS WS 2008 (2009)

 

T. Umedachi, T. Kitamura, T. Nakagaki, R. Kobayashi and A. Ishiguro : “A modular robot driven by protoplasmic streaming”, DISTRIBUTED AUTONOMOUS ROBOTIC SYSTEMS 8 (Eds. H.Asama et al.) Springer : 193-202 (2009)

 

T. Nakagaki, T. Saigusa, A. Tero and R. Kobayashi : “Effects of food amount on path selection in transport network of an amoeboid organism”, Topological Aspects of Critical Systems and Networks, World Scientific : 94-100 (2007)

 

著書

小林 亮 : 「結晶成長の数理」、自己組織化ハンドブック、分担執筆

 

小林 亮 : 「フェーズフィールドモデル」、シリーズ 数理生物学要論 巻2 「空間」の数理生物学、共立出版、分担執筆 : 167-180 (2009)

 

小林 亮、高橋 大輔 : 「ベクトル解析入門」、東京大学出版会 (2003)

 

小林 亮 : 「血管分岐系形成の数理モデル」、生物の形づくりの数理と物理, シリーズニューバイオフィジクスII、共立出版、本多久夫編 : 137-153 (2000)、分担執筆

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口頭発表

2009年度

小林 亮 : 「フェーズフィールドモデルのおもしろさ」、日本機械学会第22回計算力学講演会、金沢大学 (2009-10)

 

R. Kobayashi : “A Mathematical Model of Amoeboid Locomotion”, Reaction-Diffusion Systems: Modeling and Analysis, Universite de Paris-Sud 11, Orsay, France (2009-06)

 

2008年度

R. Kobayashi : “A Mathematical Model of Amoeboid Locomotion”, International Conference for Nonlinear Science, Sapporo Winter School, Hokkaido University (2009-02)

 

小林 亮 : 「アメーバ運動の数理モデル」、生命数理セミナー研究会、北海道虻田郡 (2009-01)

 

小林 亮 : 「アメーバ運動の数理モデル」、第46回日本生物物理学会年会、福岡国際会議場 (2008-12)

 

小林 亮 : 「アメーバ運動の数理モデル」、日本機械学会第21回計算力学講演会 CMD2008、琉球大学 (2008-11)

 

R. Kobayashi : “A Mathematical Model of Amoeboid Locomotion”, Mathematical Understanding of Complex Systems arising in Biology and Medicine, Meiji University (2008-10)

 

R. Kobayashi : “A Mathematical Model of Amoeboid Locomotion”, Dynamics Days Asia Pacific 5, Nara (2008-09)

 

R. Kobayashi, A. Tero and T. Nakagaki : “Patterns and Computations in Biological Systems -- True Slime Mold --”, Czech-Japanese Seminar in Applied Mathematics 2008, Takachiho, Miyazaki (2008-09)

 

R. Kobayashi : “A Mathematical Model of Locomoting Amoeba”, The Second China-Japan Colloquium of Mathematical Biology, Okayama (2008-08)

 

R. Kobayashi : “A Mathematical Model of Locomoting Amoeba”, European Conference on Mathematical and Theoretical Biology, Edinburgh, UK (2008-06 〜 2008-07)

 

R. Kobayashi : “A Mathematical Model of Amoeboid Locomotion”, Gordon Research Conference on Mathematical Biology and Biomathematics, Barga, Italy (2008-06)

 

2007年度

R.Kobayashi, A. Tero and T. Nakagaki : “Dynamical Synchronization in True Slime Mold - Maze Solving Amoeba -”, The 23rd Symposium of the Society of Population Ecology "Spatial Structure and Dynamics of Ecological System", Sapporo (2007-10)

 

R. Kobayashi, A. Tero, T. Nakagaki and K. Yumiki : “A Biologically Motivated Shortest Path Finding Algorithm”, The Workshop on Mathematical Modelling and Analysis of Biological Pattern Formations and the Related Topics, Nagoya (2007-09)

 

R. Kobayashi, A. Tero and T. Nakagaki : “A Biologically Motivated Shortest Path Finding Algorithm”, Mathematical Modeling and Analysis in Biological and Chemical Systems, Orsay, France (2007-09)

 

2006年度

R. Kobayashi, A. Tero and T. Nakagaki : “Patterns and Computations in Biological Systems -- Physarum Polycephalum --”, International Workshop on Information Communication Technology, Sendai International Center (2006-12)

 

小林 亮、手老 篤史、中垣 俊之 : 「生物における構造形成と情報処理 --- 真正粘菌をモデル生物として ---」、日本数学会秋期総合分科会、大阪市立大学 (2006-09)

 

R. Kobayashi and J. A. Warren : “Modeling of the evolution of 3 Dimensional polycrystalline structures”, 19th General Meeting of the International Mineralogical Association, Kobe (2006-07)

 

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